UMB Data Catalog
A project of the Health Sciences and Human Services Library-
Sleep Disturbances in Neurobehaviorally Challenged Children with Sickle Cell Disease
UMB Dataset- Authors
- Valerie E. RogersEboni I. Lance
- Description
Children with sickle cell disease (SCD) experience neurodevelopmental decline over time. They also tend to have short duration, poor quality sleep and elevated fatigue levels. This study measured sleep via actigraphy over one week and cognitive and behavioral measures in 19 children and adolescents with SCD. Aged 7-18 years, the majority of participants were referred for neurodevelopmental testing due to academic or behavioral difficulties. Data was collected from parent report, medical record, and included age, sex, race, SCD genotype, results of neuroimaging studies including brain magnetic resonance imaging (MRI) and transcranial Doppler (TCD) velocities, and current use of hydroxyl urea or chronic blood transfusion. Additionally, parents completed the Behavior Rating Inventory of Executive Function (BRIEF), participants completed the Wide Range Achievement Test (WRAT), and both completed the PedsQL Multidimensional Fatigue Scale.
- Subject
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Anemia, Sickle CellNeurodevelopmental DisordersSleep Wake Disorders
- Access Rights
- Unrestricted access